Peptide Database

Peptide NameDermaseptin-S12

Function Ontology

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Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC109H185N29O31S2

DescriptionStandard

        LWSKIKEMAATAGKAALNAVTGMV
    

Molecular Weight2461.94 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0733

GRAVY Index0.52

Hydrophobic Moment 0.47

Boman Index0.26

Instability Index6.90

Aliphatic Index 97.92

Aromaticity 0.0417

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 967.55

LogP -8.51

H-bond Donors 34.0

H-bond Acceptors 35.0

Rotatable Bonds 83.0

Heavy Atoms 171.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002309 VERIFIED: YES

Provenance & Taxonomy

OrganismAgalychnis annae [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)