Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length711 amino acids

Chemical FormulaC3342H5221N903O1045S18

DescriptionStandard

        MSIVLYIHPPHGCYVFKMEINMSDDMTVPTEGVDRGHTMVVWPARPKWGQPGAGTSIGINPDFDPTTGNGWLPEEDGYSEALPTGVPANIQAAINQVKPGHTDGSLMSADLWKLAPAAGYPWDPMVAWDPIFVYFPAQAVSDSNLSAGGLPDTIPVHTRIQDEVHDGAQFISATGSGSQPYSLPVINATSSGAYYTVGQLPGPMAPYTFSFSPTERGDLRFPRAEENASGLHPAGFTVGANTTDCIVVFPEGSGLEPLYFAMVVSLPDGPLRQRQEEENQAREKADAEAKAKAEAAAKAREELFAKAGVKTPPEYTPEMVKAAEAALGAAGAMALSQAPNTMQLSVAGNGVWTATGDVVGSLSAAIGRGIAALTASTVGPMVAAASTIFFPPPAGGGSDKVPGRDLDALFALNAQLLTGQNEKIEPGVNSVSLPVRGQLVNSNGQLAIQLLKTGEGLPAAVPVLNAVRDAATGLDRITVPAVAGVPERIILVNPAPPPARPSDTGSQDSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGLEPVYVMLSDPYGETNAKGEYSGRPYNTDKAGGPIQKLDWKTATIDHAGVEKVKLHTGRFTESDANKVMIDRLEKILKGELQPTDVDKRFYTHEIRELERYRSLGILDGVSPDDNGATWNNTHTATLEDYQLGNDEALLYTREALKAAEEQELRMLK
    

Molecular Weight75346.80 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-31.35

Net Charge (pH 7.4) -32.38

Charge Density (pH 7.0) -0.0441

GRAVY Index-0.24

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index32.98

Aliphatic Index 79.65

Aromaticity 0.0675

Extinction Coeff. Reduced 84800.00

Extinction Coeff. Oxidized 84925.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0233066 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli