Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC558H920N158O157S7

DescriptionStandard

        MVSFTQCCCQLASRQFKHPDRKRPSIGTSQQFKIIVLEMMFLWCVLVLVNLVSVATDTNAGVKVRLTQKGLEYGRQIAIASIQQKLRTIQLQDISGTERVKAVGKVQYSFTG
    

Molecular Weight12578.69 Da

Isoelectric Point (pI)9.89

Net Charge (pH 7.0)8.55

Net Charge (pH 7.4) 8.20

Charge Density (pH 7.0) 0.0763

GRAVY Index0.07

Hydrophobic Moment 0.68

Boman Index0.03

Instability Index14.54

Aliphatic Index 99.11

Aromaticity 0.0714

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5152.97

LogP -50.94

H-bond Donors 184.0

H-bond Acceptors 174.0

Rotatable Bonds 431.0

Heavy Atoms 880.0

Ring Count 12.0

Amide Bonds 125.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0172264 VERIFIED: NO

Provenance & Taxonomy

OrganismLabeo rohita [Bacterium]

FamilyBPI

Tax ID84645

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence