Peptide Database

Peptide NameCecropin-A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC306H497N87O84S

DescriptionStandard

        MNFYNIFVFVALILAITIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATARG
    

Molecular Weight6770.82 Da

Isoelectric Point (pI)10.16

Net Charge (pH 7.0)3.59

Net Charge (pH 7.4) 3.31

Charge Density (pH 7.0) 0.0570

GRAVY Index0.27

Hydrophobic Moment 0.94

Boman Index0.18

Instability Index36.01

Aliphatic Index 108.57

Aromaticity 0.0794

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2779.77

LogP -25.65

H-bond Donors 96.0

H-bond Acceptors 90.0

Rotatable Bonds 230.0

Heavy Atoms 478.0

Ring Count 7.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0146433 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyCecropin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria

RECORD: Rec_0337413 VERIFIED: NO