Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length463 amino acids

Chemical FormulaC2328H3653N601O713S16

DescriptionStandard

        MWKISCFVLFVTVFTLSRCDDPGLKLRIFQKGLDNANGAVKEFLENKIRDLRVGKLIGYGNGSLQFNISYTKLLNFTIINSSMTLVPYTGIQITISNSNATINSVWKVRNETSEVKNITVMKVSEASITMVINISKNDPEYPLFSVVNCTTDIKKIDIKLGNAIEPMFANYKEELNNEVLSLLNPQVCRAVTENFELWTTNISTFSGRYDVNRYVGINYQLVNSPVFTEKYFDVNINGSFYAINGTDRPVAPADFPFLDSNDSAMCIGISEAALNSVAQAYYDARFFRLTFTHPMINKSVAEWNGEQNSIYARGILNATKAPEFILNPKNITMNFNADLLLVTKEPNKTRVLVVTINTESSISATVSISEANSTLNVSGSLTLNSLDLNVISNQTTTNTKDEELKKSMKEFLEKPLMEYFNSKMKQGFNFTNFPFLNLVNPTLDTGEKSIQINTDAEYNTTTW
    

Molecular Weight51981.54 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-4.41

Net Charge (pH 7.4) -4.87

Charge Density (pH 7.0) -0.0095

GRAVY Index-0.15

Hydrophobic Moment 0.75

Boman Index0.06

Instability Index27.77

Aliphatic Index 89.87

Aromaticity 0.1015

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 50100.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358961 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocaecilia unicolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria