Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC754H1177N217O218S6

DescriptionStandard

        MSKVQFKPRAVTEAIFVHCSATKASMNVGLREIRQWHKEQGWLDVGYHFIIRRDGTIEEGRPVDVVGSHVKDWNSKSVGVCLVGGIDDKGRHEANFTPAQMHSLKEKLADLKDLYPDAEIKAHHDVAPKACPSFNLSRWLKTGELVTSDWG
    

Molecular Weight16962.12 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)1.19

Net Charge (pH 7.4) 0.48

Charge Density (pH 7.0) 0.0079

GRAVY Index-0.46

Hydrophobic Moment 0.75

Boman Index-0.04

Instability Index41.34

Aliphatic Index 78.08

Aromaticity 0.0795

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6972.29

LogP -66.02

H-bond Donors 245.0

H-bond Acceptors 233.0

Rotatable Bonds 564.0

Heavy Atoms 1195.0

Ring Count 31.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366724 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage PhiV-1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic