Peptide Database

Peptide NamePutative klebicin D activity protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length692 amino acids

Chemical FormulaC3136H5078N914O1004S12

DescriptionStandard

        MSTELKGPGEIAGENLGGSGANLNERPDNSTPGGGSNGTGGNDSGGSSSGYTAARRQIDAVVNDPAVKSKLSAIIKGAKAINPNAHLSITELTETGTLKLGITDISADQASALGLGNIITVHANNGFMYTGGSIETGHVLGKTPPGIGGTGGSNDSGTIAAQNKVSPDIYLSVLQGTIPNGFWLSNDKVMTRVRVAYIINGGGKGDDRTGYRDKDVEVPSLTDAWNTSKQIKADIEEAARQAEAARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARQALYKKAGILPTPSYSPEKAAAGSAALAKAGVMALNRAPAALQLTSVAGGVMTTASELAGWVASALWRGAVAVSDIAVVSPVGAMVGAFVAGFTPIPVGTGSDRVPGRDIEMLAVQARLMAAGKVSIEPGMTSVNLPVRSFITTDDDGRQSVHMVKTGVGGVSAAVPVLNAVRDEATGLDRITVPAVAGAPSRTILINPVPSGPTVPANTGNTGPVPKTPVHTGTDIRQADSIVTTTYPAAEDLAIQDFIYWQPDALVSGVEPIYVMLASPRDLPGKVTGKGEQVGDGWLDKAGEELGSPIPSQIADKLRGREFSNFNSFRRAFWKTVSDTPELSEQFDQASLGSIKLGKSSFVRKSERVGGRLKHELHHVKAIKDGGDVFDVDNLRVMTPKKHIEVHKSNGGK
    

Molecular Weight72034.17 Da

Isoelectric Point (pI)6.84

Net Charge (pH 7.0)-0.52

Net Charge (pH 7.4) -1.42

Charge Density (pH 7.0) -0.0008

GRAVY Index-0.29

Hydrophobic Moment 0.81

Boman Index0.02

Instability Index35.46

Aliphatic Index 80.84

Aromaticity 0.0434

Extinction Coeff. Reduced 53400.00

Extinction Coeff. Oxidized 53400.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013329 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella aerogenes [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence