Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC809H1227N179O253S3

DescriptionStandard

        QNNDLAEVDFSLSSLPSVFQPFIDLDLKGIVFPAGNYTDSAYEAASFTILDQSDSVLYLAFSEYFFQTSSLAYYTTGPFNITIAEETCRYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPVISLQQDSFALEIQGSLEVLAVLPDSTTQSLLTL
    

Molecular Weight17604.64 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.22

Net Charge (pH 7.4) -15.48

Charge Density (pH 7.0) -0.0957

GRAVY Index0.28

Hydrophobic Moment 0.57

Boman Index0.24

Instability Index50.70

Aliphatic Index 101.19

Aromaticity 0.1321

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6863.36

LogP -61.45

H-bond Donors 232.0

H-bond Acceptors 241.0

Rotatable Bonds 561.0

Heavy Atoms 1244.0

Ring Count 30.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009076 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvia atricapilla [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria