Peptide Database

Peptide NameBevacizumab

Function Ontology

Anticancer

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length214 amino acids

Chemical FormulaC1034H1595N273O338S6

DescriptionStandard

        DIQMTQSPSSLSASVGDRVTITCSASQDISNYLNWYQQKPGKAPKVLIYFTSSLHSGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQYSTVPWTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
    

Molecular Weight23450.74 Da

Isoelectric Point (pI)6.34

Net Charge (pH 7.0)-1.01

Net Charge (pH 7.4) -1.50

Charge Density (pH 7.0) -0.0047

GRAVY Index-0.44

Hydrophobic Moment 0.58

Boman Index-0.00

Instability Index49.45

Aliphatic Index 65.09

Aromaticity 0.1028

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205207 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10090

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-angiogenic Anticancer Monoclonal antibody Anti-VEGF

PaperPubMed-linked source references: PMID:25638326; PMID:25637137; PMID:25631483; PMID:25628268; PMID:25627091; PMID:25624888; PMID:18343240; PMID:18054637; PMID:17409907 PMID25638326;25637137;25631483;25628268;25627091;25624888;18343240;18054637;17409907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25638326/ PatentCA2145985