Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC165H261N49O50S6

DescriptionStandard

        DQYKCLKNGGICRYSPCPLYSRVEGTCYSGRAKCC
    

Molecular Weight3923.53 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.39

Charge Density (pH 7.0) 0.1056

GRAVY Index-0.55

Hydrophobic Moment 0.36

Boman Index-0.17

Instability Index24.27

Aliphatic Index 44.57

Aromaticity 0.1143

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1621.52

LogP -19.38

H-bond Donors 64.0

H-bond Acceptors 60.0

Rotatable Bonds 126.0

Heavy Atoms 270.0

Ring Count 6.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347008 VERIFIED: YES

Provenance & Taxonomy

OrganismOchotona princeps [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)