Peptide Database

Peptide NameTCTP (1-7) deletion mutant

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC42H70N10O11S

DescriptionStandard

        MIIYRDL
    

Molecular Weight923.13 Da

Isoelectric Point (pI)5.59

Net Charge (pH 7.0)-0.50

Net Charge (pH 7.4) -0.72

Charge Density (pH 7.0) -0.0714

GRAVY Index0.77

Hydrophobic Moment 0.51

Boman Index0.18

Instability Index-15.59

Aliphatic Index 167.14

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 357.35

LogP -0.12

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 30.0

Heavy Atoms 64.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398282 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTCTP

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorophore labeling

C-TermAmidation

Other ModsN-term detail: Rhodamine labeling

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa

MethodFluorescence-based uptake assay

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