Peptide Database

Peptide NameInterferon beta-1b

Function Ontology

Antiviral

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Immunomodulation ▸ Immunosuppressive

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC908H1408N246O253S6

DescriptionStandard

        MSYNLLGFLQRSSNFQSQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN
    

Molecular Weight20010.78 Da

Isoelectric Point (pI)9.02

Net Charge (pH 7.0)3.94

Net Charge (pH 7.4) 3.38

Charge Density (pH 7.0) 0.0237

GRAVY Index-0.45

Hydrophobic Moment 0.71

Boman Index-0.06

Instability Index53.95

Aliphatic Index 94.58

Aromaticity 0.1325

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8222.60

LogP -74.92

H-bond Donors 288.0

H-bond Acceptors 268.0

Rotatable Bonds 684.0

Heavy Atoms 1413.0

Ring Count 31.0

Amide Bonds 188.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320438 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Escherichia coli [Bacterium]

FamilyInterferon

Tax ID9606;562

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Immunosuppressive Antiviral

Half-Life10-20 min

PaperPubMed-linked source references: PMID:26384035; PMID:26039748; PMID:24341722; PMID:23962003; PMID:22873735; PMID:27730845; PMID:12224444; PMID:12168506 PMID26384035;26039748;24341722;23962003;22873735;27730845;12224444;12168506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26384035/ PatentCA1339707