Peptide Database

Peptide NameAntimicrobial peptide 143

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC387H630N106O97S5

DescriptionStandard

        MKVKCLLAVFLIVLIAAEHCQALFFLPSLIGGLISAIKGRRKRELGTQFRPQQKNFMRREIDLERLFAEMPDY
    

Molecular Weight8480.12 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)4.58

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0627

GRAVY Index0.18

Hydrophobic Moment 0.62

Boman Index0.05

Instability Index41.73

Aliphatic Index 110.96

Aromaticity 0.0959

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3281.70

LogP -20.23

H-bond Donors 116.0

H-bond Acceptors 108.0

Rotatable Bonds 290.0

Heavy Atoms 595.0

Ring Count 11.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107886 VERIFIED: NO

Provenance & Taxonomy

OrganismLychas mucronatus [Animal]

FamilyNon-disulfide-bridged peptide (NDBP) superfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence