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MYP_028732
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Basic Information
TPvar3
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
10 amino acids
C60H122N36O11
Standard
Sequence
RRKKRRRRRR
Physicochemical Analysis
1523.85 Da
12.00
9.76
9.55
0.9758
-4.38
0.34
-2.32
385.28
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
872.46
-10.87
37.0
21.0
59.0
107.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035165 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Multifunction
P4-R5 MAG
25 μg/mL
IC50
PaperInfection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat. PMID22319541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0120950 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 IIIB
PMID22319541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0129506 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 IIIB:inhibition of virus infection in P4-R5 MAGI cells
25 μg/mL
EC50
PaperPubMed PMID: 22319541 PMID22319541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0130218 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 22319541 PMID22319541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0350184 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 10.0%, C 40.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
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