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MYP_028725
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Basic Information
HD5(1-28)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
28 amino acids
C126H211N43O41S4
Standard
Sequence
ATCYCRTGRCATRESLSGVCEISGRLYR
Physicochemical Analysis
3112.55 Da
8.95
2.76
2.51
0.0986
-0.28
0.71
-0.21
14.33
59.29
0.0714
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1394.96
-19.00
58.0
48.0
102.0
214.0
2.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0200747 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
RECORD: Rec_0200871 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii 4-MRGN
>100 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
RECORD: Rec_0218276 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E. faecium 475747
100 μM
MIC
PaperPaneth cell alpha-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
RECORD: Rec_0225689 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2020/144166 A1 Evidence URLhttps://patents.google.com/patent/WO2020144166A1/en PatentWO 2020/144166 A1
RECORD: Rec_0350421 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii 4-MRGN
100 μM
MIC
PMID30808760 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30808760/
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