Peptide Database

Peptide NameMaftivimab

Function Ontology

Antiviral

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2167H3369N579O669S17

DescriptionStandard

        EVQLVESGGGLVQPGGSLRLSCAASGFTSSSYAMNWVRQAPGKGLEWVSTISGMGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKRGYPHSFDIWGQGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight48781.51 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 5.67

Charge Density (pH 7.0) 0.0148

GRAVY Index-0.38

Hydrophobic Moment 0.51

Boman Index0.02

Instability Index44.53

Aliphatic Index 69.73

Aromaticity 0.0893

Extinction Coeff. Reduced 72310.00

Extinction Coeff. Oxidized 72935.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123754 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Immunomodulatory

Half-LifeMaftivimab administered to healthy subjects at 50 mg/kg has a mean elimination half-life of 22.3 ± 3.09 days.[L17320]

RECORD: Rec_0160732 VERIFIED: NO