Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC836H1376N238O251S7

DescriptionStandard

        MKTQRDGPSLGRWSLVLLLLGLTMPLAVIARVLSYQEAVLRAVDVLNQRSSDANLYRLLNLDPRPTMDGDPDTPKPVSFTVKETVCPRTIQRSPEECDFKEDGLVKWCVGTVTLNQAKDSFDISCDKDKRKVAQLGDVLQKAGEKIVRGLKNIGQRIKDFFGKLTPRTES
    

Molecular Weight19001.77 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.48

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0264

GRAVY Index-0.37

Hydrophobic Moment 0.84

Boman Index-0.10

Instability Index37.17

Aliphatic Index 92.24

Aromaticity 0.0529

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7939.94

LogP -86.88

H-bond Donors 278.0

H-bond Acceptors 263.0

Rotatable Bonds 643.0

Heavy Atoms 1332.0

Ring Count 21.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222354 VERIFIED: YES

Provenance & Taxonomy

OrganismAteles fusciceps robustus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli

RECORD: Rec_0290420 VERIFIED: YES