Peptide Database

Peptide NameAvBD-12 [C5,12,17A][C27,34,35S][D3R,D8K,E21K,E29R]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC216H355N67O59

DescriptionStandard

        GPRSANHKRGLARVGNANPGKYLAKYSFRPVILSSKPLSPTPTKT
    

Molecular Weight4834.54 Da

Isoelectric Point (pI)11.61

Net Charge (pH 7.0)8.84

Net Charge (pH 7.4) 8.58

Charge Density (pH 7.0) 0.1964

GRAVY Index-0.73

Hydrophobic Moment 0.62

Boman Index-0.15

Instability Index47.40

Aliphatic Index 65.11

Aromaticity 0.0667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2028.93

LogP -24.55

H-bond Donors 71.0

H-bond Acceptors 69.0

Rotatable Bonds 153.0

Heavy Atoms 342.0

Ring Count 10.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0378322 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetPseudomonas aeruginosa ATCC 27853

Activity256 μg/mL

MethodMIC

RECORD: Rec_0386615 VERIFIED: YES