Peptide Database

Peptide NameLL-III/11

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC92H163N23O18

DescriptionStandard

        VNWKKIILGKIIKVVK
    

Molecular Weight1879.42 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.73

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.2956

GRAVY Index0.63

Hydrophobic Moment 0.51

Boman Index0.18

Instability Index-13.40

Aliphatic Index 176.25

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 688.80

LogP -0.26

H-bond Donors 24.0

H-bond Acceptors 23.0

Rotatable Bonds 68.0

Heavy Atoms 133.0

Ring Count 2.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356208 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyLasioglossin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetCCRF-CEM

Activity4±1 μM

MethodIC50

RECORD: Rec_0413745 VERIFIED: YES