Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length272 amino acids

Chemical FormulaC1332H2022N336O427S11

DescriptionStandard

        FSQICDEVSSSVSSQLQPFLQSLPGVTSIFGFLAPQGEFFSLTHRSCPPFPPPALDFPVDHDRMLYFGLSTFFFNTAGNVYYEAGAMNFTITDDMARVNWICKHKQNVFFALHLQLEKLYPDMLMMLKVSPSAAPSLTITPEVMSLSPDVDVQAFVILPNSTMAPLFVLDVVSSPQNLSSVYILEQSPNHQWSPPSSSVSLSVQDDSDGNYVIQVQSVPAVEDEEQGGFPTAENGADDTKASQVQREDRSQSDHIQTDANELSGLDETESLD
    

Molecular Weight29927.01 Da

Isoelectric Point (pI)4.16

Net Charge (pH 7.0)-24.69

Net Charge (pH 7.4) -25.30

Charge Density (pH 7.0) -0.0908

GRAVY Index-0.15

Hydrophobic Moment 0.48

Boman Index0.11

Instability Index65.92

Aliphatic Index 79.15

Aromaticity 0.0956

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404696 VERIFIED: NO

Provenance & Taxonomy

OrganismAnolis carolinensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence