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MYP_028593
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Basic Information
HeV F HRC derived peptide(447-488)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
42 amino acids
C205H335N53O71S
Standard
Sequence
PPVYTKDVDISSQISSMNQSLQQSKDYIKEAQKILDTVNPSL
Physicochemical Analysis
4710.23 Da
4.78
-1.04
-1.11
-0.0248
-0.63
0.69
-0.08
57.64
88.10
0.0476
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2039.59
-24.26
68.0
71.0
160.0
330.0
5.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0034732 VERIFIED: YES
Provenance & Taxonomy
Hendra henipavirus [Virus]
Virus-derived peptide
3052223;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Hendra virus (Fusion); HeLa
0.04 μM
Luminescence fusion assay
PaperInhibition of hendra virus fusion. | Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg GE, Moscona A. | J Virol. 2006 | PMID:16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0042355 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 66.7%, E 0.0%, T 4.8%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0074872 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Human parainfluenza virus type 3 (Fusion); HeLa
10 μM
Luminescence fusion assay
PaperInhibition of hendra virus fusion. | Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg GE, Moscona A. | J Virol. 2006 | PMID:16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
RECORD: Rec_0089344 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of fusion in HeLa cells
10 μM
IC50
PaperPubMed PMID: 16973588 PMID16973588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16973588/
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