Peptide Database

Peptide NameSPFK

Function Ontology

Antimicrobial

Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC74H121N17O15

DescriptionStandard

        PKLLKTFLSKWK
    

Molecular Weight1488.86 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.95

Net Charge (pH 7.4) 3.89

Charge Density (pH 7.0) 0.3295

GRAVY Index-0.45

Hydrophobic Moment 0.61

Boman Index-0.08

Instability Index5.30

Aliphatic Index 97.50

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 529.76

LogP -0.85

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 51.0

Heavy Atoms 106.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031640 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySPFK

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antileishmanial

TargetLeishmania donovani AG83Re (promastigote)

Activity10-4 μg/mL

MethodLD50; Microscopy (Neubauer hemocytometer motile cells counted)

RECORD: Rec_0413268 VERIFIED: YES