Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC347H517N81O85S8

DescriptionStandard

        MFFFLLQRLIENCWVLFTVVENEAASFPWSCPSLSGVCRKVCLPTELFFGPLGCGKGFLCCVSHFL
    

Molecular Weight7439.83 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-0.47

Net Charge (pH 7.4) -0.85

Charge Density (pH 7.0) -0.0072

GRAVY Index0.85

Hydrophobic Moment 0.58

Boman Index0.34

Instability Index38.75

Aliphatic Index 94.39

Aromaticity 0.1667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2575.84

LogP -14.58

H-bond Donors 95.0

H-bond Acceptors 94.0

Rotatable Bonds 231.0

Heavy Atoms 521.0

Ring Count 18.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0251751 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinodon variegatus [Bacterium]

FamilyDefensin

Tax ID28743

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence