Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length468 amino acids

Chemical FormulaC2348H3766N610O699S12

DescriptionStandard

        MWKVSCFVLFVSGLTLSHCVNPGMKLMISQKGLDFAHEVAKNFLESQVQALSIPNISGKEDIQGELKYEITNIKVEDYKIIDSSLTFVPDVGIQMAIKNSKATILSNWNVEHWTIKAKEKTTLELSEASFIIAFKISKNDTGSPLLSLNSCQSDIKKVEIKLNGPLKLIQKKYGDEKIKDVILKLLNSQICTALAEESKKWAVYVNALPVQHKIDDHVQIDYRLVNSPVFTNKYADVDVKGTFYAINNRTEPALAPAPFTLPDSSDSMLYVGISEYTLNSVAQAYFDDQALHLAFTHKQLDHIVKELDGVTANLPEARGRLRATKAPVFTLKPKNMTVELAGQIELVTKENKKPAHSEITVSITSSISADVSISESNSRLNVTGSLTLNSITLHVMSEDKTKASKFAELEKSVKNFIEKHLVPTLDGKLKRGVTIPSVPFIKLVNPISHTNEKFFQLNTDIAYNFPRM
    

Molecular Weight52109.47 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)3.55

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.0076

GRAVY Index-0.15

Hydrophobic Moment 0.68

Boman Index0.05

Instability Index31.09

Aliphatic Index 98.93

Aromaticity 0.0726

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314772 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocaecilia unicolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria