Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC746H1169N219O220S7

DescriptionStandard

        MASKVQFKPRSRTDAIFVHCSATQPSQDIGVDTIRMWHKQQGWLDVGYHFVITRDGTVESGRPVDVVGSHVKDWNSRSVGVCLVGGIDAKGKFEANFTPAQMNALRNKLDELKALYPNADIKAHHDVAPKACPSFDLQRWLKTNEMVTSDRG
    

Molecular Weight16950.05 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0198

GRAVY Index-0.45

Hydrophobic Moment 0.58

Boman Index-0.05

Instability Index39.80

Aliphatic Index 72.43

Aromaticity 0.0789

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7073.32

LogP -74.84

H-bond Donors 247.0

H-bond Acceptors 236.0

Rotatable Bonds 559.0

Heavy Atoms 1192.0

Ring Count 29.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029322 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage Ro45lw [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic