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MYP_028441
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Basic Information
NlpC/P60 family peptide (47-59)[L4,5,6A;L10K;T13A], KL6A4
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C66H124N16O14
Standard
Sequence
AAKLLLKLLLKAA
Physicochemical Analysis
1365.79 Da
10.30
2.79
2.60
0.2148
1.41
0.55
0.33
-16.89
210.77
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
490.58
-0.04
17.0
17.0
49.0
96.0
0.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HEK293 cells
PMID26385363 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26385363/
RECORD: Rec_0048367 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB1005
32 μM
MIC
PMID26385363 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26385363/
RECORD: Rec_0084346 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K88
16 μM
MIC
PMID26385363 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26385363/
RECORD: Rec_0089483 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium ATCC 14028
128 μM
MIC
PMID26385363 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26385363/
RECORD: Rec_0094807 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B.pyocyaneum ATCC 27853
>128 μM
MIC
PaperRational design of mirror-like peptides with alanine regulation.
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