Peptide Database

Peptide NamePGHPF

Function Ontology

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC27H35N7O6

DescriptionStandard

        PGHPF
    

Molecular Weight553.61 Da

Isoelectric Point (pI)7.17

Net Charge (pH 7.0)0.05

Net Charge (pH 7.4) -0.06

Charge Density (pH 7.0) 0.0091

GRAVY Index-0.80

Hydrophobic Moment 0.38

Boman Index0.30

Instability Index40.76

Aliphatic Index 0.00

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 185.62

LogP -0.89

H-bond Donors 6.0

H-bond Acceptors 7.0

Rotatable Bonds 12.0

Heavy Atoms 40.0

Ring Count 4.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202602 VERIFIED: YES

Provenance & Taxonomy

OrganismHolothuroidea [Animal]

Familysea cucumber gonad-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antioxidant SOD activation

TargetABTS at 5 mg/mL; DPPH; SOD

Activity89.8 ± 0.32 %

MethodABTS assay; DPPH radical scavenging assay; SOD activation assay