Peptide Database

Peptide NameMacropin 1 [M4K]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC69H123N17O14

DescriptionStandard

        GFGKALKLLKKVL
    

Molecular Weight1414.82 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.2889

GRAVY Index0.58

Hydrophobic Moment 0.69

Boman Index0.16

Instability Index-23.42

Aliphatic Index 150.00

Aromaticity 0.0769

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 516.60

LogP -0.90

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 52.0

Heavy Atoms 100.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343325 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetPseudomonas aeruginosa

Activity10 μM

MethodMIC

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