Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length210 amino acids

Chemical FormulaC1034H1651N257O297S9

DescriptionStandard

        VGLSEFTLNSASFGYFSAGKFQVLINESMVPPKSPVHLNTTSMGMFIPQLPKQYPNMLMTLQVYATEAPMVSLQPDVGEVSAQFGAKAFAIEPNGTQVPLFTLNIETKLRSKMWIADGKLKGNAVLDNFTLTLASSEVGTFKTDALENVVKVGINLLGLPKLNALLGDGIFLPPMKQAQLVDPVLKVEKGFLAVSADMKIVQTSRNFNTL
    

Molecular Weight22723.30 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0040

GRAVY Index0.19

Hydrophobic Moment 0.57

Boman Index0.19

Instability Index29.30

Aliphatic Index 98.86

Aromaticity 0.0810

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127651 VERIFIED: NO

Provenance & Taxonomy

OrganismIconisemion striatum [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria