Peptide Database

Peptide NameNeuromedin U-8

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC50H75N15O12

DescriptionStandard

        EFLFRPRN
    

Molecular Weight1078.22 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.67

Charge Density (pH 7.0) 0.1046

GRAVY Index-1.02

Hydrophobic Moment 0.37

Boman Index-0.38

Instability Index38.83

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 462.42

LogP -2.90

H-bond Donors 16.0

H-bond Acceptors 13.0

Rotatable Bonds 33.0

Heavy Atoms 77.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051070 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyNeuromedin U

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0253964 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyNeuromedins

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Hormone

RECORD: Rec_0403674 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/