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MYP_028274
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Basic Information
CPF-P3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
27 amino acids
C120H197N33O32
Standard
Sequence
GFGSFLGKALKAALKIGANVLGGAPQQ
Physicochemical Analysis
2614.05 Da
10.30
2.76
2.55
0.1021
0.43
0.63
0.30
16.73
101.48
0.0741
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1038.69
-10.45
34.0
35.0
88.0
185.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0271908 VERIFIED: YES
Provenance & Taxonomy
Xenopus petersii [Animal] [Animal]; Xenopus victorianus [Animal] [Animal]; Xenopus laevis sudanesis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
12.5 μM
MIC
RECORD: Rec_0272966 VERIFIED: YES
Provenance & Taxonomy
Xenopus petersii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
12.5 μM
MIC
PaperHost-defense peptides from skin secretions of the tetraploid frogs Xenopus petersii and Xenopus pygmaeus, and the octoploid frog Xenopus lenduensis (Pipidae).
RECORD: Rec_0337136 VERIFIED: YES
Provenance & Taxonomy
Xenopus petersii [Animal] [Animal]; Xenopus victorianus [Animal] [Animal]; Xenopus laevis sudanesis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
6 μM
MIC
RECORD: Rec_0355074 VERIFIED: YES
Provenance & Taxonomy
Xenopus petersii [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
6 μM
MIC
PMID22123629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22123629/
RECORD: Rec_0357221 VERIFIED: YES
Provenance & Taxonomy
Xenopus ruwenzoriensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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