Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length535 amino acids

Chemical FormulaC2530H3948N732O783S18

DescriptionStandard

        MIMATGYVLCLGDKTTCGGRIISGNPGRRAHSRPVARHGDIVTCGKHEGQYRITGGISFMTDVEGAERIPVAGTLDSVSGCPCRSGFIVTHYPAMKYESRSSGLTSSGGSPAVYGSMAGSGSALSSVAANAAKNVKTPVFAKSCLRGEGCNDAGQESEPHTNFARMAFYQAIPPADPASNYDVPQHAQSARKKKPAEDIPKPKKRSALYKWWFSNYEEVEYQRAAAAAASAANAQSALEGASVLGLIGGSAITSGTWAVSSATRLGAIAASGPGAPIAALLVGMMPGRLNEGEQDFIDRLRLEQMHEAPSRVRYTWENDSNSDAVPHGWHTPPGKDMVRVRKMEWDSSRNAYTFITEEEPRITIIWTPDSSGVNVASNTGNQNPVWIPNPVVVDPLPEDTRIEATTTPAPEEKNFADYILILPIADIPPIYIYWSKPRNGLPQNGHDYHPAPDTSEITGISGLSEAKPKTPKQGGGGKRERWIDAKGRRVYEWDSQHGELETYRASDGEHLGSVDYKTGEQLKPAVKGRNIKRYL
    

Molecular Weight57724.02 Da

Isoelectric Point (pI)7.64

Net Charge (pH 7.0)1.64

Net Charge (pH 7.4) 0.52

Charge Density (pH 7.0) 0.0031

GRAVY Index-0.51

Hydrophobic Moment 0.65

Boman Index-0.02

Instability Index42.87

Aliphatic Index 67.20

Aromaticity 0.0748

Extinction Coeff. Reduced 90300.00

Extinction Coeff. Oxidized 90675.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213039 VERIFIED: YES

Provenance & Taxonomy

OrganismErwinia sp. J780 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli