Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC124H189N35O33

DescriptionStandard

        DSIRDVSPTFNKIRRWFDGLFK
    

Molecular Weight2698.04 Da

Isoelectric Point (pI)9.98

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0801

GRAVY Index-0.69

Hydrophobic Moment 0.81

Boman Index-0.21

Instability Index101.64

Aliphatic Index 66.36

Aromaticity 0.1818

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1134.84

LogP -9.32

H-bond Donors 41.0

H-bond Acceptors 35.0

Rotatable Bonds 88.0

Heavy Atoms 192.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0433060 VERIFIED: YES

Provenance & Taxonomy

OrganismLactobacillus casei ATCC 334 [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Cytotoxic Pro-apoptotic

TargetSW480 human colorectal cancer cells

Activity40 μg/mL

MethodIC50 (MTT cell viability assay)

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