Peptide Database

Peptide NameS100A12

Function Ontology

Anticancer

Antimicrobial

Wound healing/Regeneration ▸ Wound healing

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC471H744N126O142

DescriptionStandard

        TKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE
    

Molecular Weight10443.70 Da

Isoelectric Point (pI)5.82

Net Charge (pH 7.0)-4.05

Net Charge (pH 7.4) -4.59

Charge Density (pH 7.0) -0.0445

GRAVY Index-0.43

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index22.90

Aliphatic Index 100.77

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4369.20

LogP -37.13

H-bond Donors 146.0

H-bond Acceptors 144.0

Rotatable Bonds 365.0

Heavy Atoms 739.0

Ring Count 13.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0040302 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Other Modsallo-residue reported

Bio-Activity Profile

Function

Antimicrobial Wound healing Anticancer

TargetH. pylori. 750 ug/ml S100A12 protein, H. pylori growth was repressed by 40%