Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC776H1243N221O224S5

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTKDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQVLEKFAKHYMKQLGLPDFGPASQDKIALQLIRECKALADIDEGRIHEAIRKCRSRWASLPGAGYGQHEQKIEKLIEVFKKAGGVALD
    

Molecular Weight17412.84 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.33

Charge Density (pH 7.0) 0.0503

GRAVY Index-0.53

Hydrophobic Moment 0.74

Boman Index-0.09

Instability Index35.08

Aliphatic Index 81.99

Aromaticity 0.0833

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7232.67

LogP -67.63

H-bond Donors 252.0

H-bond Acceptors 241.0

Rotatable Bonds 600.0

Heavy Atoms 1226.0

Ring Count 23.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0355194 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage nomine [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic