Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2362H3707N691O703S15

DescriptionStandard

        MRAPLGWIGSGPSPEQIAREKRAVMMAERKAAQEEEARRLAEERERNRVFAKSCLRGEGCNDAGEQQEPHTNFAPMGIYQAVPQTDPVTDTEAPQRAQTAKKKTWVAPEDIPKPKKRSALWKWWNGHHEEMDYQRAVEEAERAQRARAAIAGASVLRPVAGNFAIRGTWAVVGEAATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPHGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPNHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEEKDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKYEADHMPSRAAVDAYLRANYPLLDDAEILALTDQVAAIVIPKEIHQKISETYGKRNSPAQIELDSRNLRAAVDRNLDAIKPALKEYGATEGQIEAARAKMHKLNGGMGLYK
    

Molecular Weight53512.89 Da

Isoelectric Point (pI)6.27

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -4.43

Charge Density (pH 7.0) -0.0074

GRAVY Index-0.68

Hydrophobic Moment 0.77

Boman Index-0.11

Instability Index49.47

Aliphatic Index 71.24

Aromaticity 0.0735

Extinction Coeff. Reduced 75860.00

Extinction Coeff. Oxidized 75985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230581 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli