Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC1008H1509N221O298S9

DescriptionStandard

        VDDLAEVDYSLNSLPAVFQPFIDLDLKGTVYPAGNYTGLPYVAAPFTIPDQSDSMLYLAFSEYFFQTYSFAYYTAGAFNITIAEEVKFGKCFCLFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEEDSFTVEIQGSMEVFAVLPDSTNQSLFTTNIAANASIALNIFDQKLMGSLCLNR
    

Molecular Weight21779.65 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.28

Net Charge (pH 7.4) -14.60

Charge Density (pH 7.0) -0.0729

GRAVY Index0.37

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index43.22

Aliphatic Index 94.08

Aromaticity 0.1531

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8201.78

LogP -90.54

H-bond Donors 279.0

H-bond Acceptors 293.0

Rotatable Bonds 690.0

Heavy Atoms 1536.0

Ring Count 41.0

Amide Bonds 211.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361117 VERIFIED: NO

Provenance & Taxonomy

OrganismPiaya cayana [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria