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MYP_028143
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Basic Information
F8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C66H111N23O12
Standard
Sequence
AARIILRFRFR
Physicochemical Analysis
1418.73 Da
12.00
3.80
3.61
0.3451
0.36
0.50
-0.24
44.11
124.55
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
601.92
-3.04
24.0
16.0
47.0
101.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0130329 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 29213
2 μM
MIC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0152601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells [10% hemolysis >128 microM]
128 μM
Hemolysis
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0160532 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 29213
4 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0170248 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium C77-31
8 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
RECORD: Rec_0188538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Ranacyclin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K88
8 μM
MBC
PMID30958004 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30958004/
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