‹ ›
MYP_028134
← PREVIOUS NEXT → BACK
Basic Information
Casein beta [074-076], beta-Casokinin II
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Lipid metabolism ▸ Cholesterol-lowering
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
3 amino acids
C16H27N3O4
Standard
Sequence
IPP
Physicochemical Analysis
325.40 Da
5.53
-0.24
-0.44
-0.0800
0.43
0.42
0.54
61.27
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
103.94
0.43
2.0
4.0
5.0
23.0
2.0
2.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0287199 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
5.15 μM
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0306822 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
RP-HPLC
Human blood plasma (oral), in vivo; ~1800 s
PMID17374660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17374660/
RECORD: Rec_0314768 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Nitric oxide-modulating
PaperCharacterization of casein derived peptide bioactivity: Differential effects on angiotensin-converting enzyme inhibition and cytokine and nitric oxide production | Adams, C. et al. | DOI: 10.3168/jds.2019-17976 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0330275 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
kappa-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
5 μM
IC50
PaperPurification and Characterization of Angiotensin I-Converting Enzyme Inhibitors from Sour Milk | Nakamura, Y. et al. | DOI: 10.3168/jds.S0022-0302(95)76689-9 Evidence URLhttps://www.uniprot.org/uniprotkb/P02668/entry
RECORD: Rec_0347970 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
ACE-inhibitory peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
5 μM
IC50
PaperInhibition of angiotensin-converting enzyme by synthetic peptide fragments of human ?-casein PMID1368540 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1368540/
FIRST PREV 1 ... 7 8 9 10 11 NEXT LAST
Showing 5 records on this page · Page 9 of 11