Peptide Database

Peptide NameSLAY-screened peptide P4079

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H169N29O28S

DescriptionStandard

        RPFQVASGLLVFLCSAIRTTN
    

Molecular Weight2293.69 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0833

GRAVY Index0.71

Hydrophobic Moment 0.44

Boman Index0.19

Instability Index17.12

Aliphatic Index 111.43

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 927.43

LogP -9.40

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 72.0

Heavy Atoms 161.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0406855 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/