Peptide Database

Peptide Nameromiplostim

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length269 amino acids

Chemical FormulaC1317H2049N361O395S9

DescriptionStandard

        MDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGGIEGPTLRQWLAARAGGGGGGGGIEGPTLRQWLAARA
    

Molecular Weight29548.12 Da

Isoelectric Point (pI)8.14

Net Charge (pH 7.0)2.08

Net Charge (pH 7.4) 1.35

Charge Density (pH 7.0) 0.0077

GRAVY Index-0.53

Hydrophobic Moment 0.48

Boman Index-0.02

Instability Index50.13

Aliphatic Index 70.22

Aromaticity 0.0818

Extinction Coeff. Reduced 46410.00

Extinction Coeff. Oxidized 46785.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008063 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetThrombopoietin receptor (Human)