Peptide Database

Peptide NameBombinins BLP-7 GH-2 [Cleaved into: Bombinin-like peptide 7 (BLP-7); Bombinin GH-2]

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC705H1161N201O217S4

DescriptionStandard

        MNFKYIVAVSFLIASTYARSVKNDEQSLSQRDVLEEESLREIRGIGGALLSAGKSALKGLAKGLAEHFANGKRTAEEHEVMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLFTKKEKRILGPVLDLVGRALRGLLKKIG
    

Molecular Weight16053.24 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.66

Charge Density (pH 7.0) -0.0020

GRAVY Index-0.35

Hydrophobic Moment 0.82

Boman Index-0.08

Instability Index44.00

Aliphatic Index 96.25

Aromaticity 0.0556

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6824.30

LogP -65.98

H-bond Donors 239.0

H-bond Acceptors 223.0

Rotatable Bonds 566.0

Heavy Atoms 1127.0

Ring Count 12.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015203 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetMicrococcus luteus

RECORD: Rec_0125277 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetSaccharomyces cerevisiae

RECORD: Rec_0196935 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetCandida albicans

RECORD: Rec_0264110 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetEscherichia coli

RECORD: Rec_0362608 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetP. acnes

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