Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1845 amino acids

Chemical FormulaC8642H13244N2518O2866S25

DescriptionStandard

        MGIGDFVNSLGDKIEDGLESATEKVGQAYNTVLDAESKVAKAVGADGLSNWLDDLGDKVVDATGGAVPEKQLGQTTDPKELIRGDPAKISEVAEHVAKIGTAIDQTGDALRKIDVAEWSGEASSAFHDEYAKQPKLWWDGADAMGKAKTALDAWYHEVTAAQAKAADAIAKWEAADREERDRKNAWNAQTDEQRKGKNLTDTWTDIRNEARAILNGARTQRDNAANSAVTAITAATETAPTEPPFLSRWGSNFEDLGAAIEHAKINFSSGLLTSLTGMVQFVRSVTPFDIYNMTHPAEYMSKMSDMGTGMVIAAADPKATAAAMLSTFKTNPSEALGALTGDVLTTVATGGAGGVAKGAATTVNRASEVVDAANTGRNVLDNAAGAAGRHAPETPSAPTQPAAHVPDNPSTPSSNPAGNTGDSPATNPAGAASDSAGPNAAGQAGDPPSTNPADTPNTNPNAAADDSVPANNGDGTNPETAAPTNPRDTEPGSPTPDTGSPENGSASPNGTDESPTGKPTPDSDGGSPNQDSPTPAHNDSSPDQHDNSPTPDGDNTPGDQDSGSPTTNPDNDASPGDTDDVTNPGSHDGDGNTPDPNNNPELRAGHDNGGNGQDSAGQAGQDKPPETDSTDDQTTKVGDPVNAANGEFLLPITDLELPGILRLALKRSHHSNYRFGRWFGPSWSATLDMRVVVEADCVTVIFEDGMLLPYPHAEVGVGVEPITGGQRWKLTRTDIGGYRLWDPERELVWHFAPEPTLAGVDTLLGNYAISAITDRHHNRIRFHYNSNGDPTEVTHSGGYRVVLDCADARVTAISVADQSGEFETLTRIREFGYTRGDLTSVVNGVGGTTRFTYDDHHRMLSWTDSNGSSVTNTFDESGRVIAQRGTDGVMNADFEYLELGDGTGRLTRITDSRGGVTGFGFDNDLRLRDLLAPDGGHRHIEYNAARKPLKIIEPDGAITRFEYTAEGDVARKIRADGTDISIEYAYPNRPSTITNPDGTTSHREWDKAGNLVAVTNPAGARTQYSHNACGAVAEVRDPDGAITRIETDLAGLPVAMIDPYGARTTIRRDPFGRPAEVTDPLGGITHYKWTPEGRPARRTDPDGFAESWTYDGENNLLAHTNRNGAITRYTYCGFDRVASRTDPDGSTTRYLYDTESRLIAVINPLGQRWTYEYDLAGRLVSESNYTGATTTYTRTSTGKIGSVTPATGITRHHRYDALGNLTSITADSGEYLAYTYDAAGRILTASNGTDEICTHKLEFTYTATGEIATQTLDDQPALVNDYDHRGRRIRRTTPTRTVTTWRHNALSQVTALNADGTDITFTHDPMGRLTQWCIGELQIDRTFTPSGDVAAQEVTGFPSTAFSLDFGDTPLARPAPFALRRDDYSYRADGYLTNHTITRPNAPTVRKTYALDPIGRVSTITRDSTVSEAYEYDPLSNITASFSDDADDADDADDAGPDHTAHAAMDGREYHNNLLVRDGRNHYYYDPAGRLIRKVTTRISRKPAVWHYRYNAFDQLTDVYTPDQQWWRYTFDPLGRRVSKQLTLAGEQSPTTTSRYTWDGTHLIEESTEDGVYAWQYQPGSFTPLLQRRPKAGSPQWNSMAILTDLVGSPIGLVDPKTGARDSEVTASNLWGKTVWSQPASTPLRFPGQYFDPETGFHYNYQRTFDPAVGRYLTSDPLGLAPSPNSYLYPHNPTRYIDPLGLQPYDPRNQPGTATGGEDLPSVGPGDQWLRGSEGNAGWVPGQVADALRGQSFDSFSDFRQQFWRTVADDPDLMSQFSRNNQNLMANGNAPFAAEGQHVGGAGRYNLHHVNPIHNGGGVYDLDNLAVVTPRFHAEVLDPTFHYNR
    

Molecular Weight199070.39 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-88.06

Net Charge (pH 7.4) -91.21

Charge Density (pH 7.0) -0.0477

GRAVY Index-0.68

Hydrophobic Moment 0.84

Boman Index-0.06

Instability Index33.85

Aliphatic Index 61.54

Aromaticity 0.0780

Extinction Coeff. Reduced 271360.00

Extinction Coeff. Oxidized 271735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403449 VERIFIED: NO

Provenance & Taxonomy

OrganismNocardia mangyaensis [other]

FamilyColicin pyosin nuclease

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Hydrolase Non-hemolytic