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MYP_028045
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Basic Information
Insulin-like growth factor I
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
70 amino acids
C332H520N94O102S7
Standard
Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKSA
Physicochemical Analysis
7684.70 Da
7.76
0.71
0.40
0.0101
-0.31
0.46
-0.06
64.49
58.57
0.1000
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3147.16
-35.45
116.0
110.0
247.0
535.0
12.0
72.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010444 VERIFIED: NO
Provenance & Taxonomy
Capra hircus [Animal]
Insulin-like growth factor
9925
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0012080 VERIFIED: NO
Provenance & Taxonomy
Capra hircus [Animal]
Insulin-like growth factor
9925
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0130921 VERIFIED: NO
Provenance & Taxonomy
Capra hircus [Animal]
Insulin
9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
Evidence URLhttps://www.uniprot.org/uniprotkb/IGF1_CAPHI/entry
RECORD: Rec_0290212 VERIFIED: NO
Provenance & Taxonomy
Capra hircus [Animal]
Insulin-like growth factor
9925
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
bone-derived osteoblastic (PyMS) cells
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour