Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC588H921N161O164S4

DescriptionStandard

        AQEPLAQEPMLLLALSEFVANSAAFAYFTAGALRRNITSDSLPRRFPLQLRTKSVGLFSPQLQELYPDQPMELQLWARRQPLFSCRPDALHGTLYGSAEASVMLPNGSRAPAFLLHI
    

Molecular Weight12997.84 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)0.98

Net Charge (pH 7.4) 0.65

Charge Density (pH 7.0) 0.0083

GRAVY Index-0.03

Hydrophobic Moment 0.58

Boman Index0.08

Instability Index74.49

Aliphatic Index 93.59

Aromaticity 0.0940

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5152.10

LogP -46.66

H-bond Donors 176.0

H-bond Acceptors 171.0

Rotatable Bonds 413.0

Heavy Atoms 917.0

Ring Count 25.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247047 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocolius indicus (Red-faced mousebird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria