Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length213 amino acids

Chemical FormulaC1047H1631N269O313S9

DescriptionStandard

        MLPSVMVVFAILSCSRGENPAVQVTLTDKWLQYVKHVGAGWIQDKLEHISFPDISSDVDILIGHVYYTLSSIRIMKCDLPEPVLEFYQSTGLKTSIVGLNVALVGDWRTSFGIIHDSGSFDMAILSVSLTSVVQLGRDPDGHLSITSISCEPQVGNVDIRFHGGASFIFQPFVDHFTGKIVSVLQSNICPHVQTAIDDLESHLQAMSSTTSSF
    

Molecular Weight23283.35 Da

Isoelectric Point (pI)5.14

Net Charge (pH 7.0)-9.73

Net Charge (pH 7.4) -10.50

Charge Density (pH 7.0) -0.0457

GRAVY Index0.28

Hydrophobic Moment 0.58

Boman Index0.21

Instability Index41.46

Aliphatic Index 103.29

Aromaticity 0.0845

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238695 VERIFIED: NO

Provenance & Taxonomy

OrganismNothobranchius korthausae [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria