Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC766H1178N210O225S10

DescriptionStandard

        MLCVFYHNLGESRDETFRKESFSLLLQFLNTYGFIKIILLPRPCLNIQSFYYLAYRGEKKCWNKSGHCRRNCEAEEVTQETCKNHRVCCIPANKVPSNKHPPMTTIPAFHNSPSDFTNAIETVTTIDYFEVNDKEPGTQTPIPEIRHSS
    

Molecular Weight17249.47 Da

Isoelectric Point (pI)7.59

Net Charge (pH 7.0)0.97

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0065

GRAVY Index-0.52

Hydrophobic Moment 0.56

Boman Index-0.06

Instability Index58.37

Aliphatic Index 67.38

Aromaticity 0.1074

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7000.27

LogP -70.10

H-bond Donors 246.0

H-bond Acceptors 242.0

Rotatable Bonds 558.0

Heavy Atoms 1211.0

Ring Count 34.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228120 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal