Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length447 amino acids

Chemical FormulaC2258H3524N556O659S18

DescriptionStandard

        MESEKILVLCGCFLLWNPLIQSTQLYPGIKVRITQKGLDYGMQAGMEAIELIVKKNGIPDFKGSESLEFLKVDYVDYNFSNIKINTFSFPNISLTPVSGTGVKVLSNHGSTNVSMAWEVTSPLFRDEGGAALFLAEIFFSGLVNLSRSDTGHPTMKLEDCYIRVGHAHISFSGEFSVLYNSFAEPMEKPILKNLNKKLCPIIMDRFEDINANISSLEVVTKFGEDILLDYSLLEPPEITQSSIDLNLKGTFYQVGNLTDPPFQPVPFTLPDRSDSMLYIGISEYFLRSAAFTYFLTGAFNITLTTKELSKHLIQNPQGIGSLFSQIAELYIMTQPLMMRVLTTEPPVVSLEPNNFTLNIPGSVVMLTKPKNATEEAIVSMDFVASTDVGLAILGQKLICSLSLNRFRLSGPESNRSSIEVLRFENILSSILHFGVFPLANGFPSGFY
    

Molecular Weight49580.63 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-11.96

Net Charge (pH 7.4) -12.66

Charge Density (pH 7.0) -0.0268

GRAVY Index0.13

Hydrophobic Moment 0.62

Boman Index0.17

Instability Index38.61

Aliphatic Index 99.19

Aromaticity 0.1029

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0098440 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria