Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC780H1230N204O244S15

DescriptionStandard

        MNILMLTFIICGLLTQVTKGSFEPPKCWKNNIGHCRRRCLDTERYILLCRNKLSCCIYIIISHEYTRRPAFPMIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSETTTPETTMTPTETATSETMPPPSQRALTHN
    

Molecular Weight17850.31 Da

Isoelectric Point (pI)5.31

Net Charge (pH 7.0)-5.19

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.0331

GRAVY Index-0.32

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index66.22

Aliphatic Index 67.07

Aromaticity 0.0764

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7124.31

LogP -75.53

H-bond Donors 253.0

H-bond Acceptors 258.0

Rotatable Bonds 569.0

Heavy Atoms 1243.0

Ring Count 31.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359790 VERIFIED: NO

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyDefensin

Tax ID9597

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence