Peptide Database

Peptide NameThrombopoietin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC127H211N41O35S

DescriptionStandard

        SPAPPACDPRLLNKLLRDDHVLHGRL
    

Molecular Weight2904.35 Da

Isoelectric Point (pI)7.99

Net Charge (pH 7.0)0.63

Net Charge (pH 7.4) 0.30

Charge Density (pH 7.0) 0.0241

GRAVY Index-0.47

Hydrophobic Moment 0.76

Boman Index-0.14

Instability Index86.82

Aliphatic Index 108.85

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1199.96

LogP -10.78

H-bond Donors 41.0

H-bond Acceptors 39.0

Rotatable Bonds 90.0

Heavy Atoms 204.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198878 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyThrombopoietin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour